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Med J Aust. 1996 Aug 5;165(3):164-7.

Oral retinoids and pregnancy.

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  • 1South Australian Health Commission, Public and Environmental Health Service, Adelaide.


The oral retinoids isotretinoin and etretinate are uniquely effective in the treatment of severe cystic acne and keratinisation disorders. Because of their known teratogenicity, there are strict prescription guidelines, but exposure during pregnancy still occurs. A dedicated effort by women and their clinicians is required, involving patient selection, education and informed consent, detailed contraceptive counselling, and careful monitoring and management, including pregnancy testing before commencement of therapy.

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