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Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6631-4.

Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin.

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  • 1Institute of Anatomy, University of Würzburg, Germany.

Abstract

The alpha-subunit of the trimeric G-protein complex specific for taste receptor cells of the tongue, alpha-gustducin, is described here to be also expressed in the stomach and intestine. The alpha-gustducin-containing cells were identified as brush cells that are scattered throughout the surface epithelium of the gut and share structural features of taste receptor cells of the tongue. These findings provide clues to the long-sought molecular and cellular basis for chemoreception in the gut.

PMID:
8692869
PMCID:
PMC39077
[PubMed - indexed for MEDLINE]
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