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Eur J Surg. 1996 Jan;162(1):11-4.

Propranolol reduces the anxiety associated with day case surgery.

Author information

1
Dept. of Surgery, Adelaide Hospital, Dublin, Ireland.

Abstract

OBJECTIVE:

To find out if propranolol, a non-cardioselective beta-blocker, can reduce the anxiety associated with day case surgery.

DESIGN:

Prospective randomized double blind trial.

SETTING:

University hospital, Ireland.

SUBJECTS:

An unselected group of 53 patients undergoing day case surgery.

INTERVENTION:

Subjects randomised to receive either propranolol (10 mg) or placebo on the morning of operation.

MAIN OUTCOME MEASURES:

Blood pressure; pulse, anxiety, pain score and patient satisfaction.

RESULTS:

Mean (SD) Hospital Anxiety and Depression score was significantly lower in the propranolol group than in the control group (2.5 (0.7) compared with 4.6 (0.7), p < 0.0001) before discharge.

CONCLUSION:

A low dose of propranolol given on the morning of day case surgery significantly reduced patients' anxiety.

PMID:
8679756
[Indexed for MEDLINE]

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