A 73-year-old woman with a lymphoproliferative disorder had successive stages of reactive lymphadenopathy in sequence, a multifocal type of Castleman's disease and angioimmunoblastic lymphadenopathy. The disease ran an aggressive course and was associated with disseminated Kaposi's sarcoma. The linkage between the various types of lymphoproliferative disorders that presented in the same patient, as well as the association with Kaposi's sarcoma, are discussed.