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Biochem Biophys Res Commun. 1996 Jun 14;223(2):229-33.

Dynamin II binds to the trans-Golgi network.

Author information

1
Division of Cell Biology, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

Abstract

Two dynamin II-specific antibodies were used to detect dynamin II attached to highly purified Golgi membranes of HepG2 cells. Within the Golgi apparatus dynamin II is predominantly localized to the trans-Golgi network, as shown by immunoelectron microscopy. Increased binding of dynamin II to the trans-Golgi network in the presence of GTP-gamma-S and a reduced binding upon stimulation of secretion by phorbolester indicates that dynamin II may have a function in post-Golgi vesicle transport.

PMID:
8670264
DOI:
10.1006/bbrc.1996.0876
[Indexed for MEDLINE]

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