Format

Send to

Choose Destination
Anticancer Res. 1995 Nov-Dec;15(6B):2797-8.

Lack of expression of c-erbB-2 oncoprotein in human esophageal squamous cell carcinomas.

Author information

1
Department of Pathology, Norwegian Radium Hospital, Oslo, Norway. zhenhes@radium.uio.no

Abstract

Fifty-one cases of esophageal squamous cell carcinoma were immunohistochemically investigated with monoclonal c-erbB 2 oncoprotein antibody. No tumor showed plasma membrane immunostaining for c-erbB-2 protein. Occasionally, unspecific cytoplasmic staining was found in minor tumor cell populations. The present results show that c-erbB-2 oncoprotein is not overexpressed in esophageal squamous cell carcinomas and does not play a central role in the tumorigenesis.

PMID:
8669867
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center