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Gene. 1996 Feb 12;168(2):243-6.

Cloning and expression of the cDNA encoding rat tissue inhibitor of metalloproteinase 3 (TIMP-3).

Author information

1
Laboratory for Surgical Research, Children's Hospital, Boston, MA 02115, USA.

Abstract

We have cloned the cDNA encoding the rat tissue inhibitor of metalloproteinase 3 (TIMP-3) by a PCR cloning method. Sequence analysis reveals an open reading frame containing 211 amino acids that show 99% identity to mouse TIMP-3 and 95% identity to human TIMP-3, respectively. High-level expression of TIMP-3 was detected in rat kidney, lungs and heart.

PMID:
8654952
DOI:
10.1016/0378-1119(95)00783-0
[Indexed for MEDLINE]

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