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J Am Acad Dermatol. 1996 Feb;34(2 Pt 1):253-6.

Confluent and reticulated papillomatosis: response to minocycline.

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1
Department of Dermatology, Walter Reed Army Medical Center, Washington, DC 20307, USA.

Abstract

BACKGROUND:

Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed.

OBJECTIVE:

We attempted to evaluate the effectiveness of oral minocycline.

METHODS:

Nine patients with CRP were treated with oral minocycline, 50 mg twice a day, for 6 weeks. The average follow-up period was 11 months. Recurrence rate, side effects, and effectiveness of therapy were assessed.

RESULTS:

All patients except two had a 90% to 100% response to therapy. Recurrences were noted in three patients, all of whom responded to re-treatment with minocycline. None of the nine patients had an adverse reaction.

CONCLUSION:

Minocycline, 50 mg twice a day, is safe and effective for CRP.

PMID:
8642090
[Indexed for MEDLINE]
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