Format

Send to

Choose Destination
Nat Genet. 1996 Jun;13(2):154-60.

Minisatellite diversity supports a recent African origin for modern humans.

Author information

1
Department of Genetics, University of Leicester, UK.

Abstract

In a study of human diversity at a highly variable locus, we have mapped the internal structures of tandem-repetitive alleles from different populations at the minisatellite MS205 (D16S309). The results give an unusually detailed view of the different allelic structures represented on modern human chromosomes, and of the ancestral relationships between them. There was a clear difference in allelic diversity between African and non-African populations. A restricted set of allele families was found in non-African populations, and formed a subset of the much greater diversity seen on African chromosomes. The data strongly support a recent African origin for modern human diversity at this locus.

PMID:
8640220
DOI:
10.1038/ng0696-154
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center