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J Pediatr. 1996 Feb;128(2):275-8.

Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.

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  • 1Clinica Pediatrica, Università di Pavia, Istituto di Ricovero e Cura a Carattere Scientifico S. Matteo, Italy.

Abstract

A macrophage activation syndrome, possibly related to methotrexate toxicity, developed in a boy with systemic juvenile rheumatoid arthritis. Corticosteroid administration was ineffective, whereas a prompt response to cyclosporine was observed. Two months later, Pneumocystis carinii pneumonia developed.

PMID:
8636829
[PubMed - indexed for MEDLINE]
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