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Radiology. 1996 Mar;198(3):855-9.

Articular cartilage volume in the knee: semiautomated determination from three-dimensional reformations of MR images.

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1
Department of Radiology, Albany Medical College, New York 12208, USA.

Abstract

PURPOSE:

To determine the accuracy of semiautomated quantification of articular cartilage volume from three-dimensional (3D) reformations of magnetic resonance (MR) images.

MATERIALS AND METHODS:

Sagittal, fat-suppressed, 3D, spoiled gradient-recalled-echo MR imaging of two bovine and two human cadaver knees was performed. Articular cartilage volume was calculated from 3D reformations of the MR images by using a semiautomated program written at the authors' institution. Calculated volumes were compared with directly measured volumes of the surgically removed articular cartilage.

RESULTS:

The percentage of error of the MR imaging-determined volumes was 6.53% +/- 4.75 (mean +/- standard deviation). A strong correlation between the two sets of observations was shown (r=.997). Linear regression showed the calculated volumes to be highly accurate (slope=1.002, P>.25). Repeated reformations yielded volumes that were reproducible (mean absolute error, 0.013 mL +/- 0.019) and not significantly different from the measured volume (P>.10).

CONCLUSION:

Semiautomated quantification of knee articular cartilage from MR images yields highly accurate cartilage volumes.

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