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FEBS Lett. 1996 Mar 25;383(1-2):119-23.

Production and crystallization of MHC class I B allele single peptide complexes.

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1
Laboratory of Molecular Biophysics, Oxford, UK.

Abstract

Major histocompatibility complex class I B alleles, HLA B8, B53 and B3501 have been cloned, expressed, refolded and crystallized in specific complexes with a number of different 8-mer and 9-mer peptides. For some of these crystallization was initiated by cross-seeding between different B allele complexes. All crystallize in the space group P212121, with similar unit cell dimensions of approximately 52 A X 81 A X 112 A, contain one complex per asymmetric unit and diffract to approximately 2.0 A resolution.

PMID:
8612777
DOI:
10.1016/0014-5793(96)00226-8
[Indexed for MEDLINE]
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