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Ann Allergy Asthma Immunol. 1996 Apr;76(4):376-8.

A fatality from idiopathic anaphylaxis.

Author information

1
Department of Medicine, Northwestern Memorial Hospital, Chicago, Illinois, USA.

Abstract

BACKGROUND:

Idiopathic anaphylaxis by definition is a form of anaphylaxis where no identifiable stimulus can be found. In our series of over 350 patients with idiopathic anaphylaxis there have been no reported deaths.

OBJECTIVE:

To report the clinical course of the first fatality in our series from idiopathic anaphylaxis.

METHODS:

A patient was evaluated for idiopathic anaphylaxis and started on our previously published protocol of corticosteroids, sympathomimetics, and antihistamines.

RESULTS:

Despite following our protocol--which has been effective in decreasing the number of emergency room visits, hospitalizations, and intensive care unit admissions--controlling the disease, and placing a high percentage of patients into remission, the patient with idiopathic anaphylaxis died unexpectedly after experiencing symptoms similar to previous episodes of idiopathic anaphylaxis.

CONCLUSION:

This is the first reported fatality from idiopathic anaphylaxis in our extensive series.

PMID:
8612123
DOI:
10.1016/S1081-1206(10)60042-7
[Indexed for MEDLINE]
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