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Am J Psychiatry. 1996 Mar;153(3):411-3.

Change in thyroid hormone levels following response to cognitive therapy for major depression.

Author information

1
Department of Psychiatry, McMaster University, Hamilton, Ont., Canada.

Abstract

OBJECTIVE:

Various somatic antidepressant treatments of depression are associated with substantial but limited decreases in T4 levels. This study examined changes in patients' thyroid hormone levels during a period of cognitive behavior therapy.

METHOD:

Thyroid hormone levels of 30 patients with major depressive disorder were measured before and after they received 20 weekly sessions of cognitive behavior therapy.

RESULTS:

There were significant decreases in measures of T4 in the 17 responders to cognitive behavior therapy and increases in the 13 nonresponders.

CONCLUSIONS:

Cognitive behavior therapy has an effect on the thyroid axis similar to that of somatic antidepressant treatments.

PMID:
8610831
DOI:
10.1176/ajp.153.3.411
[Indexed for MEDLINE]
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