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Surg Clin North Am. 1996 Apr;76(2):221-30.

The woman at high risk for breast cancer. Importance of hyperplasia.

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Department of Pathology, Vanderbilt University, Nashville, Tennessee, USA.


In summary, some histopathologically identifiable lesions within the human breast indicate later development of invasive breast cancer at an increased incidence over that of the general population. Many of these may be regarded as markers of increased risk because they are indicative of cancers presenting anywhere in either breast, whereas the noncomedo DCIS lesions are unique in indicating a high likelihood of invasive disease at the same site of detection of the initial high-risk lesion (Table 2).

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