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Nature. 1996 May 2;381(6577):86-9.

A human RNA polymerase II complex associated with SRB and DNA-repair proteins.

Author information

1
Howard Hughes Medical Institute, Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854-5635, USA.

Erratum in

  • Nature 1996 Nov 28;384(6607):384.

Abstract

We report here the isolation of a human RNA polymerase II complex containing a subset of the basal transcription factors and the human homologues of the yeast SRB (for suppressors of RNA polymerase B) proteins. The complex contains transcriptional coactivators and increases the activation of transcription. In addition, some components of the RNA polymerase II complex participate in DNA repair.

PMID:
8609996
DOI:
10.1038/381086a0
[Indexed for MEDLINE]

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