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Genomics. 1995 Nov 1;30(1):81-3.

Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23.

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  • 1Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Abstract

ASCL1, the human achaete-scute homolog, is a helix-loop-helix transcription factor that was previously assigned to chromosome 12 using a rodent-human somatic hybrid panel. We now placed this gene on a yeast artificial chromosome contig encompassing position 119 cM of the Généthon genetic map between the two genes phenylalanine hydroxylase (PAH) and tumor rejection antigen 1 (TRA1). We also localized ASCL1 in the 12q22-q23 cytogenetic interval by using fluorescence in situ hybridization.

PMID:
8595908
DOI:
10.1006/geno.1995.0012
[PubMed - indexed for MEDLINE]
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