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Eur J Gastroenterol Hepatol. 1995 Aug;7 Suppl 1:S11-5.

Helicobacter pylori infection and chronological extension of atrophic gastritis.

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1
Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.

Abstract

OBJECTIVES:

To determine the relationship between Helicobacter pylori infection and chronological extension of atrophic gastritis.

PATIENTS AND METHODS:

We studied 137 non-ulcer patients. The extent of atrophic gastritis was assessed endoscopically and scored on a scale of 1-6 (endoscopic score) using the atrophic pattern system. H. pylori infection was assessed by enzyme-linked immunosorbent assay with serum anti-H. pylori immunoglobulin G. The correlation between patient age and endoscopic score was determined for H. pylori-positive and -negative patients.

RESULTS:

A positive correlation between age and extent of atrophic gastritis was found in both H. pylori-positive and -negative patients. In groups of patients aged 20-29 and 30-39 years, those with H. pylori had more extensive atrophic gastritis than those without H. pylori.

CONCLUSIONS:

Chronological extension of atrophic gastritis was found in patients with and without H. pylori infection.

PMID:
8574729
[Indexed for MEDLINE]

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