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Curr Opin Cell Biol. 1995 Oct;7(5):634-40.

Signal transduction of beta-catenin.

Author information

1
Cellular Biochemistry & Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Abstract

Beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in beta-catenin signaling.

PMID:
8573337
DOI:
10.1016/0955-0674(95)80104-9
[Indexed for MEDLINE]

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