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Fertil Steril. 1996 Feb;65(2):250-3.

Frequency of abnormal karyotypes among abortuses from women with and without a history of recurrent spontaneous abortion.

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1
Grupo De Reproducción y Genetica AGN y Asociados Hospital Angeles Del Pedregal, México, D.F., México.

Abstract

OBJECTIVE:

To compare the frequency of chromosomal abnormalities in products of conception from women with and without a history of recurrent spontaneous abortion.

DESIGN:

Retrospective analysis of prospectively collected material.

SETTING:

Private practice at the Genetics and IVF Institute, Fairfax, Virginia and Grupo de Reproducción AGY Asociados, México City, México.

PATIENTS:

Women with (n = 94) and without (n = 130) a history of recurrent spontaneous abortion who had a spontaneous abortion between January 1, 1992 and November 1, 1994.

INTERVENTION:

Chromosomal analysis performed on products of conception using standard G-banding technique.

MAIN OUTCOME MEASURE:

The percentage of chromosomal abnormalities among products of conception from women with and without recurrent spontaneous abortion was compared.

RESULTS:

Among products of conception from women with recurrent spontaneous abortion, 57% (54/94) had abnormal and 43% (40/94) had normal chromosome analyses. Products of conception from women without recurrent spontaneous abortion had abnormal chromosome analyses in 57% (74/130) and normal results in 43% (56/130).

CONCLUSIONS:

No differences in frequency of abnormal karyotype were observed in products of conception from women with recurrent spontaneous abortion compared with women without recurrent spontaneous abortion.

PMID:
8566242
[Indexed for MEDLINE]
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