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Eur J Clin Microbiol Infect Dis. 1995 Aug;14(8):710-3.

Testing of saliva and serum for HIV in high-risk populations. Ad Hoc Group for the Comparative Saliva and Serum Study.

Author information

1
AIDS Programme, Department of Health, Generalitat de Catalunya, Barcelona, Spain.

Abstract

Paired samples of saliva and serum from 286 high-risk subjects were tested for HIV using two commercial enzyme immunoassays following the same WHO testing strategy supplemented with a Western blot technique. Agreement between HIV testing in both sample types was 98.9% (95% confidence interval: 97.7-100). The sensitivity of an EIA (Wellcozyme GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7% (151/153). These results support previous data showing that in some situations saliva might be an effective alternative to serum for HIV testing.

PMID:
8565992
DOI:
10.1007/bf01690881
[Indexed for MEDLINE]

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