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Trends Microbiol. 1995 Oct;3(10):381-6.

Role of O-antigen variation in the immune response.

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Dept of Microbiology (G08), University of Sydney, NSW, Australia.


The O antigen is an extremely variable surface polysaccharide of Gram-negative bacteria. This variation is thought to allow the various clones of a species each to present a surface that offers a selective advantage in the niche occupied by that clone. The interactions between O antigen and the immune system are central to determining the selective advantage of each clone.

[Indexed for MEDLINE]

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