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Jpn Heart J. 1995 Sep;36(5):681-8.

Systemic amyloidosis following ankylosing spondylitis associated with congestive heart failure. A case report.

Author information

1
Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine, Saitama, Japan.

Abstract

We report the case of a 38-year-old man who developed fatal, systemic amyloidosis following ankylosing spondylitis. He was admitted for symptoms of congestive heart failure. Based on parotid gland biopsy and echocardiography, he was diagnosed as having systemic amyloidosis following active ankylosing spondylitis. However, the clinical course was rapidly progressive and eventually the patient died of acute necrotizing pancreatitis. The association has been reported thus far in a limited number of cases worldwide. The literature has featured localized lesions and a benign clinical course of the amyloidosis. This case, the first report from Japan, indicates that the amyloidosis associated with ankylosing spondylitis might exhibit a rapidly progressive clinical course, thereby suggesting that in such a case, meticulous treatment is required.

PMID:
8558773
[Indexed for MEDLINE]

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