Ten-year changes in the obesity, abdominal adiposity, and serum lipoprotein cholesterol measures of Western Samoan men

J Clin Epidemiol. 1995 Dec;48(12):1485-93. doi: 10.1016/0895-4356(95)00060-7.

Abstract

Previously reported associations between abdominal adiposity and coronary heart disease (CHD) may be mediated through serum lipids. In the present longitudinal study, 43 Western Samoan men who participated in a 1982 study were recontacted for a second determination of anthropometric and serum lipoprotein cholesterol levels. The men showed dramatic increases in weight (mean change +/- SD: 10.5 +/- 8.8 kg), abdominal circumference (10.0 +/- 7.6 cm), total cholesterol (49.5 +/- 26.4 mg/dl), and non-HDL cholesterol (53.1 +/- 26.6 mg/dl). A new indicator was used to estimate changes in abdominal adiposity: the residual from the regression of change in the abdominal circumference on change in body weight (the AR). The AR was significantly correlated with changes in total (r = 0.38) and non-HDL cholesterol (r = 0.39). Changes in HDL cholesterol were correlated with changes in weight only (r = -0.37). These bivariate relations remained significant in multiple linear regression analyses. These longitudinal results are the first to suggest changes in abdominal adiposity are related to changes in total and non-HDL cholesterol levels.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abdomen / pathology
  • Adipose Tissue / pathology*
  • Adult
  • Anthropometry
  • Body Constitution
  • Cholesterol / blood
  • Cholesterol, HDL / blood*
  • Cholesterol, LDL / blood*
  • Coronary Disease / epidemiology
  • Follow-Up Studies
  • Humans
  • Independent State of Samoa / epidemiology
  • Longitudinal Studies
  • Male
  • Obesity / blood
  • Obesity / epidemiology
  • Obesity / pathology*
  • Risk Factors
  • Weight Gain

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Cholesterol