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Scand J Infect Dis. 1995;27(3):241-3.

Intravenous immunoglobulin treatment in children with Guillain-Barre syndrome.

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Department of Pediatrics, Ondokuz Mayis University School of Medicine, Samsun, Turkey.


Guillain-Barre syndrome is an acquired demyelinating polyneuropathy that is presumed to be immune-mediated. On the basis of this assumption, intravenous immunoglobulin (IVIG) has been used in the treatment of Guillain-Barre syndrome in recent years and found to be effective. To test this we performed a randomized study in patients with Guillain-Barre syndrome by giving IVIG (1 g/kg body weight per day over 2 consecutive days) in 9 children who were compared with 9 patients who were observed but not given specific therapy. We concluded that intravenous immunoglobulin is a safe and effective treatment for childhood Guillain-Barre syndrome which shortens the time to recovery.

[Indexed for MEDLINE]

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