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Gene. 1995 Dec 1;166(1):117-9.

Cloning and sequence analysis of the Corynebacterium diphtheriae dtxR homologue from Streptomyces lividans and S. pilosus encoding a putative iron repressor protein.

Author information

1
Animal Health Biotechnology, Ciba-Geigy AG, Basel, Switzerland.

Abstract

The iron-regulated promoter involved in desferrioxamine B synthesis of Streptomyces pilosus contains a region homologous to the iron repressor (DtxR)-binding site of the diphtheria toxin gene promoter in Corynebacterium diphtheriae [Günter et al., J. Bacteriol. 175 (1993) 3295-3302]. Here, we report the cloning and sequencing of the putative Streptomyces iron repressor gene, homologous to dtxR of C. diphtheriae. The N-terminal 139 amino acids of the deduced protein are 73% identical to DtxR.

PMID:
8529874
DOI:
10.1016/0378-1119(95)00628-7
[Indexed for MEDLINE]

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