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Trends Microbiol. 1995 Aug;3(8):295-9.

Virulence factors of Cryptococcus neoformans.

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Dept of Microbiology, School of Medicine, University of Nevada, Reno 59557, USA.


Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-mediated host defenses. Cryptococcus neoformans produces several virulence factors, most notably the polysaccharide capsule and phenol oxidase. Molecular studies of cryptococcal virulence factors have contributed to our understanding of the pathobiology of this yeast, and will enable the identification of new targets for antifungal therapy.

[Indexed for MEDLINE]

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