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FEBS Lett. 1995 Nov 27;376(1-2):108-12.

M-caveolin, a muscle-specific caveolin-related protein.

Author information

1
European Molecular Biology Laboratory, Heidelberg, Germany.

Corrected and republished in

Abstract

Caveolae, small invaginations of the plasma membrane, are a characteristic feature of many mammalian cells. The best-characterised caveolar protein is the integral membrane protein, VIP21-caveolin. We now describe a novel homologue of VIP21-caveolin, M-caveolin, which is expressed exclusively in muscle. M-caveolin was shown to be expressed in differentiated myotubes but not myoblasts. Epitope-tagged M-caveolin expressed in non-muscle cells was targetted to surface caveolae where it colocalized with endogenous VIP21-caveolin. M-caveolin may play a specialised role in the caveolae of muscle cells.

PMID:
8521953
DOI:
10.1016/0014-5793(95)01256-7
[Indexed for MEDLINE]
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