Format

Send to

Choose Destination
Trends Microbiol. 1995 Sep;3(9):351-6.

Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis.

Author information

1
Dept of Microbiology, University of Texas Health Science Center at San Antonio 78284-7758, USA.

Abstract

During chronic infections in cystic fibrosis, persistence of Pseudomonas aeruginosa is associated with conversion into forms that are associated with conversion into forms that are characterized by a mucoid colony morphology, rough lipopolysaccharide and, paradoxically, decreased systemic virulence. The mutations underlying these changes occur in global regulators, such as alternative sigma factors and their accessory elements.

PMID:
8520888
DOI:
10.1016/s0966-842x(00)88974-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center