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Trends Microbiol. 1995 Sep;3(9):338-45.

CD46-mediated measles virus entry: a first key to host-range specificity.

Author information

1
Laboratoire Immunité et Infections Virales, I.V.M.C. CNRS-UCBL UMR30, Faculté de Médecine Alexis Carrel, Lyon, France.

Abstract

Humans are the sole natural host of measles virus. The identification of CD46 as a virus receptor and of the involvement of moesin sheds some light on the molecular events occurring during virus entry into the cell. Knowledge of the key role of CD46 paves the way to creating transgenic mice sensitive to measles virus infection.

PMID:
8520886
DOI:
10.1016/s0966-842x(00)88972-6
[Indexed for MEDLINE]

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