Format

Send to

Choose Destination
See comment in PubMed Commons below
J Antibiot (Tokyo). 1993 May;46(5):833-9.

Synthesis and antibacterial activity of cephalosporins having a catechol in the C3 side chain.

Author information

1
Birstol-Myers Squibb Research Institute, Tokyo, Japan.

Abstract

Cephalosporins having a catechol through a variety of linkages to the C3 position and a different C7 side chain were prepared. Among them, 3-(catechol-4- ylcarbonyloxy)methylcephalosporin (14) and 3-[(E)-3-(catechol-4-ylcarbonyloxy)-1-propen-1-yl]cephalospo rin (10) showed excellent activity against Gram-negative activity including ceftazidime-resistant Escherichia coli, Pseudomonas aeruginosa, Xanthomonas maltophilia and Pseudomonas cepacia.

PMID:
8514638
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for J-STAGE, Japan Science and Technology Information Aggregator, Electronic
    Loading ...
    Support Center