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Radiology. 1993 Jul;188(1):277-82.

Multisection proton MR spectroscopic imaging of the brain.

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Laboratory of Diagnostic Radiology Research, National Institutes of Health, Bethesda, MD 20892.


The authors developed a hydrogen-1 proton magnetic resonance (MR) imaging method in which metabolic information is acquired by obtaining multiple sections through the brain. A spin-echo sequence is used for section selection, an octangular outer volume saturation pulse for lipid suppression, and a chemical-shift-selective saturation pulse for water suppression. High-quality maps of choline, creatine, and N-acetylaspartate were obtained in six studies performed in four volunteers. Water and lipid signal from the skull area was well suppressed by the pulse sequence used.

[Indexed for MEDLINE]

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