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Lancet. 1979 Mar 3;1(8114):472-4.

Dried-blood spot screening for cystic fibrosis in the newborn.


Serum-immunoreactive-trypsin (I.R.T.) was measured in children with cystic fibrosis (C.F.) and a variety of controls. In the first few months of life all C.F. children had a raised serum-I.R.T. A dried blood-spot assay for I.R.T. was established and has potential as a screening test for C.F. in the newborn.

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