Abstract
The promoter for human cholesterol 7-alpha hydroxylase has been cloned and sequenced. In the regions previously described, our sequence agrees well with one report but not with another. At position -469, we find a widespread MaeII polymorphism. At -2636, there is an Alu sequence flanked by runs of adenines. Upstream of the Alu sequence, there is a cyclophilin pseudogene oriented in the opposite direction.
MeSH terms
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Amino Acid Isomerases / genetics*
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Base Sequence
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Carrier Proteins / genetics*
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Cholesterol 7-alpha-Hydroxylase / genetics*
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Cloning, Molecular
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Humans
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Molecular Sequence Data
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Peptidylprolyl Isomerase
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Polymorphism, Genetic
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Promoter Regions, Genetic*
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Pseudogenes*
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Repetitive Sequences, Nucleic Acid*
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Sequence Alignment
Substances
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Carrier Proteins
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Cholesterol 7-alpha-Hydroxylase
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Amino Acid Isomerases
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Peptidylprolyl Isomerase
Associated data
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GENBANK/L04613
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GENBANK/L04614
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GENBANK/L04615
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GENBANK/L04616
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GENBANK/L07951
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GENBANK/L10669
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GENBANK/L17031
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GENBANK/L17032
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GENBANK/L17033
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GENBANK/X61667