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Immunol Today. 1993 Apr;14(4):155-7.

A case for cytokines as effector molecules in the resolution of virus infection.

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1
John Curtin School of Medical Research, Australian National University, Canberra, ACT.

Abstract

Some cytokines are known to have potent antiviral activity in vitro, and recent work shows that severely immunodeficient mice, which lack conventional effector T cells, can still recover from virus infection provided these factors are present at sites of virus replication. Here Alistair Ramsay, Janet Ruby and Ian Ramshaw discuss these findings and raise fundamental questions concerning the physiological role of cytotoxic T cells in the resolution of virus infection.

PMID:
8499074
DOI:
10.1016/0167-5699(93)90277-R
[Indexed for MEDLINE]
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