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Ann Neurol. 1993 Jun;33(6):649-52.

Coexistence of hereditary motor and sensory neuropathy type Ia and IgM paraproteinemic neuropathy.

Author information

1
University Department of Clinical Neurology, Institute of Neurology, London, UK.

Abstract

A patient with minimal motor dysfunction dating from early childhood developed more rapidly progressive distal weakness and positive sensory symptoms due to peripheral neuropathy in the fourth decade of life. DNA analysis showed the partial duplication of chromosome 17p associated with hereditary motor and sensory neuropathy type Ia. In addition, the patient had an IgM paraproteinemia and the typical morphological features of IgM paraproteinemic neuropathy on nerve biopsy.

PMID:
8498845
DOI:
10.1002/ana.410330615
[Indexed for MEDLINE]

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