Format

Send to

Choose Destination
Am J Ophthalmol. 1993 May 15;115(5):640-3.

Eosinophil granule major basic protein deposition in corneal ulcers associated with vernal keratoconjunctivitis.

Author information

1
Department of Ophthalmology, University of Texas Medical Branch, Galveston 77555.

Abstract

An indirect immunofluorescence assay detected eosinophil granule major basic protein in the inflammatory debris covering deepithelialized cornea in two patients with vernal keratoconjunctivitis. A slight degree of non-specific fluorescence was present in the control autopsy corneas. High concentrations of the eosinophil granule major basic protein inhibit epithelial migration and protein synthesis, whereas low concentrations affect epithelial migration. The results suggest participation of eosinophil granule major basic protein in the ulcerative process.

PMID:
8488918
DOI:
10.1016/s0002-9394(14)71463-1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center