The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses

A A Bukreyev; V E Volchkov; V M Blinov; S V Netesov

doi:10.1016/0014-5793(93)81107-b

The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses

FEBS Lett. 1993 May 3;322(1):41-6. doi: 10.1016/0014-5793(93)81107-b.

Authors

A A Bukreyev¹, V E Volchkov, V M Blinov, S V Netesov

Affiliation

¹ Institute of Molecular Biology, Koltsovo, Novosibirsk Region, Russian Federation.

PMID: 8482365
DOI: 10.1016/0014-5793(93)81107-b

Abstract

The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.

MeSH terms

Amino Acid Sequence
Base Sequence
DNA, Viral
Ebolavirus / genetics*
Marburgvirus / genetics*
Molecular Sequence Data
Open Reading Frames
RNA, Viral / genetics
Sequence Homology, Amino Acid
Viral Matrix Proteins
Viral Proteins / genetics*
Viral Regulatory and Accessory Proteins

Substances

DNA, Viral
RNA, Viral
VP35 protein, filovirus
VP40 protein, virus
Viral Matrix Proteins
Viral Proteins
Viral Regulatory and Accessory Proteins

Associated data

GENBANK/X61274
GENBANK/X64406