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J Rheumatol. 1993 Mar;20(3):579-81.

Development of a disease activity score based on judgment in clinical practice by rheumatologists.

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Department of Rheumatology, University Hospital Nijmegen, The Netherlands.


In a prospective study of up to 3 years' duration of 113 patients with early rheumatoid arthritis a disease activity score (DAS) was developed based on the clinical judgment of 6 rheumatologists. The patients were divided in groups with high and low disease activity according to explicit rules. By various statistical methods, including discriminant analysis and multiple regression analysis, a DAS could be defined. This DAS is a continuous measure consisting of the variables Ritchie articular index, number of swollen joints, erythrocyte sedimentation rate and general health measured on a visual analog scale.

[Indexed for MEDLINE]

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