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Nature. 1993 Apr 22;362(6422):722-8.

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Author information

1
Children's Hospital, Dana-Farber Cancer Institute, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115.

Abstract

Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.

PMID:
8469283
DOI:
10.1038/362722a0
[Indexed for MEDLINE]

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