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JAMA. 1993 Apr 21;269(15):2017-22.

Altered fates--counseling families with inherited breast cancer.



Breo profiles Barbara Weber, M.D., and Francis Collins, M.D., of the University of Michigan School of Medicine's breast cancer clinic, and their work isolating and identifying genetic markers for the gene that means an 85% lifetime risk of developing breast cancer, as well as a significantly higher risk of ovarian cancer. Their discovery is expected to revolutionize women's health care and to present society with daunting economic, ethical, and counseling issues. [Collins discovered the genes that cause cystic fibrosis, neurofibromatosis, and Huntington's disease. He was named director of the National Center for Human Genome Research at the National Institutes of Health in April 1993].

[Indexed for MEDLINE]

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