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J Am Acad Dermatol. 1993 Apr;28(4):585-90.

Abnormal lymph drainage in patients with chronic venous leg ulcers.

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1
Department of Dermatology, St George's Hospital, London, England.

Abstract

BACKGROUND:

Edema often occurs in association with venous leg ulcers.

OBJECTIVE:

Our purpose was to assess lymphatic function in the legs of patients with venous leg ulcers.

METHODS:

Quantitative lymphoscintigraphy was performed in 22 normal control subjects, 32 patients with venous leg ulcers, and 7 patients with varicose veins only.

RESULTS:

Lymph drainage declined with age in the normal controls (r = -0.57; p = 0.0001). Lymphatic function was reduced in the ulcerated legs compared with normal limbs (age < 65 years; p < 0.0001) and in edematous legs compared with nonedematous legs (age > 65 years; ulcerated legs, p = 0.016; nonulcerated legs, p = 0.021). Lymph drainage was lower in the legs of patients with varicose veins only (p = 0.004).

CONCLUSION:

Impaired lymphatic function is associated with both venous leg ulcers and chronic venous hypertension.

PMID:
8463459
[Indexed for MEDLINE]
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