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Trends Genet. 1993 Feb;9(2):61-5.

High-frequency phenotypic switching in Candida albicans.

Author information

1
Department of Biological Sciences, University of Iowa, Iowa City 52242-1324.

Abstract

Most strains of Candida albicans are capable of switching spontaneously and at high frequencies between a number of phenotypes distinguished by colony morphology. Unlike switching in many other microbial pathogens, switching in C. albicans is pleiotropic, affecting several morphological and physiological parameters. Recently, the first phase-specific genes were identified and shown to be regulated at the level of gene transcription.

PMID:
8456504
DOI:
10.1016/0168-9525(93)90189-O
[Indexed for MEDLINE]

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