Format

Send to

Choose Destination
See comment in PubMed Commons below
Surgery. 1993 Apr;113(4):389-94.

The role of surgery in the treatment of nonregionally recurrent melanoma.

Author information

1
Department of Surgery, John Wayne Cancer Clinic, Jonsson Comprehensive Cancer Center, University of California, Los Angeles.

Abstract

BACKGROUND:

Between 1971 and 1989, 144 patients underwent 183 surgical procedures for resection of nonregional metastatic melanoma.

METHODS:

Thirty-six patients with subcutaneous or nodal metastases, 46 patients with pulmonary metastases, 17 patients with brain metastases, 19 with gastrointestinal metastases, and 26 patients with miscellaneous sites of metastatic involvement underwent resection.

RESULTS:

The overall 5- and 10-year actuarial survival rates were 20% and 14%, respectively. A single postoperative death occurred in a patient operated on for palliative treatment of gastrointestinal metastases.

CONCLUSIONS:

Cox regression analysis suggests that patients with a solitary metastasis confined to the subcutaneous, nonregional lymph nodes or lung are most likely to benefit from aggressive surgical intervention. Surgical intervention represents a potentially important modality in the management of selected patients with nonregional metastatic melanoma.

PMID:
8456394
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center