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Curr Opin Genet Dev. 1993 Feb;3(1):44-9.

The role of c-myc in cell growth.

Author information

1
Biochemistry of the Cell Nucleus Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, UK.

Abstract

Recent experiments have established that the c-myc oncogene encodes a sequence-specific DNA-binding protein that interacts with a specific intracellular partner, Max, and probably manifests its effects through transcriptional modulation. In addition, the range of biological functions attributed to expression of c-myc has grown to include not only transformation and mitogenesis but also cell death.

PMID:
8453273
DOI:
10.1016/s0959-437x(05)80339-9
[Indexed for MEDLINE]

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