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Curr Opin Cell Biol. 1993 Feb;5(1):82-7.

Dystrophin and the membrane skeleton.

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1
University of Wisconsin, Department of Physiology, Madison 53706.

Abstract

Recent studies have confirmed several predictions concerning the structure and possible function of dystrophin, including a direct interaction with F-actin and an indirect interaction with laminin via linkage through a transmembrane protein complex. The results of the past year support a role for dystrophin in linking the actin cytoskeleton with the extracellular matrix in striated muscle, but they have not explained its function in other tissues.

PMID:
8448034
[Indexed for MEDLINE]
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