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Curr Opin Cell Biol. 1993 Feb;5(1):12-6.

Molecular biology of neuronal intermediate filaments.

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Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York 10032.


In the past few years, several neuronal intermediate filament proteins have been characterized. While ongoing investigations have continued to shed light on their developmental expression, the importance of different domains of the proteins for assembly, the elements in their genes necessary for tissue-specific expression, and the role of phosphorylation of neurofilaments, the function(s) of these structures remain a matter of speculation.

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