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Ann Neurol. 1993 Feb;33(2):152-8.

Pathological findings at the site of conduction block in multifocal motor neuropathy.

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1
Department of Neurology, Kyoto University Hospital, Japan.

Abstract

We report on 2 patients with multifocal motor neuropathy with focal conduction block involving motor but not sensory fibers at the site of nerve swelling. A nerve biopsy specimen from adjacent to the enlargement in 1 patient showed a perivascular area containing scattered demyelinated axons surrounded by small onion bulbs. The observed pathological findings are consistent with the conduction block considered characteristic of this neuropathy, although the underlying immunological mechanisms for selectivity and persistence remain undetermined.

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PMID:
8434876
DOI:
10.1002/ana.410330204
[Indexed for MEDLINE]

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