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Cancer Genet Cytogenet. 1993 Jan;65(1):1-6.

Translocation (X;1) in papillary renal cell carcinoma. A new cytogenetic subtype.

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Southwest Biomedical Research Institute and Genetrix, Inc., Scottsdale, Arizona 85251.


We report a consistent t(X;1)(p11.2;q21) that was observed in four cases of papillary renal tumors. In one of the cases, two cells showed the cytogenetic abnormality as the only change, whereas the other cases showed additional chromosomal anomalies particularly involving chromosomes 7 and 17. One identical t(X;1) has been reported previously in a papillary renal cell carcinoma. To date, all of the patients carrying this translocation have been males.

[Indexed for MEDLINE]

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