Format

Send to

Choose Destination
See comment in PubMed Commons below
Diabetes Care. 1993 Jan;16(1):184-6.

Successful treatment of severe refractory sulfonylurea-induced hypoglycemia with octreotide.

Author information

1
Diabetic Clinic, General Hospital, Birmingham, United Kingdom.

Abstract

OBJECTIVE:

To test the clinical use of octreotide in the treatment of sulfonylurea-induced hypoglycemia.

RESEARCH DESIGN AND METHODS:

A case is reported of sulfonylurea-induced hypoglycemic coma in a nondiabetic subject, which was complicated by relapse of hypoglycemia after resuscitation with intravenous dextrose. Subcutaneous octreotide, 50 micrograms 12 hourly, suppressed stimulated endogenous insulin secretion, thereby preventing a further recurrence of hypoglycemia.

RESULTS:

No adverse effects of treatment were observed.

CONCLUSIONS:

These results suggest a significant role for octreotide as an adjunct to intravenous dextrose in the management of severe and refractory cases of sulfonylurea-induced hypoglycemia.

PMID:
8422773
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center